Back Cover: Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action (ChemMedChem 18/2016)
نویسندگان
چکیده
منابع مشابه
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling
BACKGROUND Artemisinin resistance observed in Southeast Asia threatens the continued use of artemisinin-based combination therapy in endemic countries. Additionally, the diversity of chemical mode of action in the global portfolio of marketed antimalarials is extremely limited. Addressing the urgent need for the development of new antimalarials, a chemical class of potent antimalarial compounds...
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ژورنال
عنوان ژورنال: ChemMedChem
سال: 2016
ISSN: 1860-7179
DOI: 10.1002/cmdc.201600436